This can be done programmatically and while I have seen several slightly different solutions to this problem, I have found that the below script does the trick on Windows.
Save the code below to a batch command file (.bat) and place it in the root of you KNIME workspace folder.
@ECHO OFF
ECHO This script will automatically reset all workflows
PAUSE
DEL /S /F "data.zip"
DEL /S /F "data.xml"
DEL /S /F ".savedWithData"
DEL /S /F "db_session.xml"
DEL /S /F "*.table"
ECHO.
ECHO The next step is to empty the recycle bin
PAUSE
PowerShell Clear-RecycleBin -force -ErrorAction:Ignore
ECHO.
PAUSE
Once saved in the correct folder, you can execute the file and it will reset every node in every workflow in your workspace and then empty your recycle bin.
Although I have used this many times, you should still make sure to have a backup of your workflows before using this the first time and then ensure that everything still works as intended.