Hello all! I am trying to run a script that calculates the centered log ratio. What makes my situation potentially different, from past questions on the same topic is that the Python Scrip Node used to work flawlessly with the same script. But now as the screenshot shows, the Python Node fails to work. Im not sure what is different now than in the past. I do have installed the basic Python extension. [image] Here is the flow variables which I have not changed. . . . [image] By training I am a geoscientist. . . . Im taking baby steps into data science by teaching myself. I hope someone can help me. Many thanks! ~Cole K.

Hi Cole, He is a link to download - Box (only available for a few days) The script can be used to fix all Python environments bundled with a KNIME installation: ./fix_knime_python_envs.sh /Applications/path/to/KNIME.app Or to fix an external conda environment: ./fix_knime_python_envs.sh /path/to/conda/env What you need to do is Open terminal and navigate to the script’s location Make the script executable chmod +x fix_knime_python_envs.sh Find the correct path to KNIME.app ( You may need to escape spaces using backslashes (\ ) or quote the entire path:) Example: ./fix_knime_python_envs.sh /Applications/KNIME\ 5.4.3.app If you get a permission denied error run with sudo but in general I would recommend asking ChatGPT what it recommends doing about the error you got. If everything is correct it will start checking libraries in the Knime installation. Let me know if that worked.

Execution failed: Could not connect to the Python process.

KNIME Analytics Platform

BenceKeseru April 10, 2025, 12:00pm 8

Great to hear it worked. Here you can find the official forum post about the issue by our developers:

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