Hello @alishitz,
Regarding your first question about the WebPortal, the WebPortal is available in our Commercial offering. The KNIME Serverr (software) has this capability in addition to automation, collaboration, security, and monitoring.
I am not sure about the answer for your second question but you could try installing the R package. Here are some tips. I am not familiar with the KNIME4NGS extension.
Regards,
Cynthia