Machine Learning: Combine fingerpirnt with descriptors

Is there any way to perfrom machine learning with a chemical fingerprint and descriptors in the same node?

Tree Ensemble learner only allows fingerprint or descriptors but not a combination of them. Weka does not seem to have support for fingerprints at all.

What are my options?

Is it meaningful to convert fingerprints to numbers (long) and use those numbers in Weka liek normal descriptors?



Yes beginner, I expand fingerprints, use remove high variance node and then use remaining binary descriptors. Not bad for classification models

Shouldn't that be low variance filter node? I'd also add a linear correlation node and a correlation filter.