Protein structural diversity analysis

Protein X ray structures are extracted from different sources and analyzed. They are aligned by structure and the sequences are renumbered accordingly. The statistical analysis of Ramachandran angles used as alignment free descriptors is performed as well as the selection of the most meaningful descriptors. Most significant angles are projected onto protein structure. This workflow was developed by Marc Bianciotto at Sanofi. [Requires: Prime, Vernalis extensions and R extensions (with CircStats library). Optional: Erlwood extensions]


This is a companion discussion topic for the original entry at https://kni.me/w/e0MdbnH98Tx48u5l