# Python Script Node KNIME - PLS/PLS-DA algorithm

**URL:** <https://forum.knime.com/t/python-script-node-knime-pls-pls-da-algorithm/49465>\
**Category:** KNIME Analytics Platform\
**Created:** [November 30, 2022, 8:45am UTC](https://forum.knime.com/t/python-script-node-knime-pls-pls-da-algorithm/49465 "2022-11-30T08:45:41Z")\
**Posts on this page:** 1\
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**Author:** ![alessandro\_mac](https://forum-cdn.knime.com/user_avatar/forum.knime.com/alessandro_mac/32/45623_2.png) [@alessandro\_mac](https://forum.knime.com/u/alessandro_mac)\
**Post date:** [November 30, 2022, 9:07am UTC](https://forum.knime.com/t/python-script-node-knime-pls-pls-da-algorithm/49465/3 "2022-11-30T09:07:56Z")

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Hi @Artem,

Thank you very much for your quick reply!

Great, thanks, I missed that simple detail!

I’ve also checked the Schrödinger implementation again, but unless you download also the software, I think it shouldn’t work. I receive a _license error_ (as also shown here: [PLS, OPLS, PLS-DA, ...](https://forum.knime.com/t/pls-opls-pls-da/35682))

As a reference:

> **[How do I install the Schrödinger KNIME extensions from a new Schrödinger...](https://www.schrodinger.com/kb/1085)**
>
> Use the KNIME interface to install the extensions (Help → Install New Software), as described in Installing and Updating KNIME Extensions. The latest update site for Knime 3.x is available from content.schrodinger.com/knime/previous and for Knime 4.0...

Where they say:

> _The extensions will not work without a Schrödinger software installation._  
> And I’m not sure it would work on a web based app.

About the implementation, very gladly!  
As soon as I have a working example I’ll share it here!

Thanks very much again!  
Best,  
Alessandro

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