scaffold node improvement

Community Extensions
1

dear all,

 

Is it possible to change in the murko scaffold node in a scaffold finder follwing not only the murko definitions and if is possible to include the definitions of Pollock (J. Chem. Inf. Model. 2008, 48, 1304) and Schuffenhauer (J. Chem. Inf. Model.2007, 47, 47). This of course has the possibility to chose the rule...as Strip-it of silicos-it do?

Colud be a better improvements in the scaffold finder strategy.

 

thanks

2

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