Hi @adesinoh and welcome to the KNIME community !
Below you will find a workflow which provides a full Tanimoto matrix distance:
20220216 Pikairos Tanimoto Similarity Matrix.knwf (110.1 KB)
The extra work needed here was to transform a Half-Diagonal Distance matrix provided by the -Distance Matrix Calculate- node into a full Distance Matrix with “Ones” diagonal included.
This can be generalized to a Euclidean Distance Matrix where the diagonal should be made of Zeros.
Hope it helps.
Best wishes,
Ael