Hi Stefan, thanks for the answer,
Both installation (mine that can open and the non functioning) are 3.7.2.
The log does not contain any error message (see below). Or do you spot anything suspect ?
I was wondering if it could be a limitation on the file size ?
But in the end I prefer saving separatly images and table as csv. I am not bound to KNIME to quickly check the data, it’s possibly safer for long term storage and I can further copy/move a fraction of the data rather than having a monolithic 2Gb table 
2019-06-11 16:30:53,205 : DEBUG : main : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: IDLE
2019-06-11 16:30:53,208 : DEBUG : main : Node : Table Reader : 0:1 : Configure succeeded. (Table Reader)
2019-06-11 16:30:53,208 : DEBUG : main : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: CONFIGURED
2019-06-11 16:30:53,208 : DEBUG : main : NodeContainer : Table Reader : 0:1 : KNIME_project 0 has new state: CONFIGURED
2019-06-11 16:30:54,609 : DEBUG : main : ExecuteAction : : : Creating execution job for 1 node(s)...
2019-06-11 16:30:54,610 : DEBUG : main : NodeContainer : : : Table Reader 0:1 has new state: CONFIGURED_MARKEDFOREXEC
2019-06-11 16:30:54,610 : DEBUG : main : NodeContainer : : : Table Reader 0:1 has new state: CONFIGURED_QUEUED
2019-06-11 16:30:54,610 : DEBUG : main : NodeContainer : : : KNIME_project 0 has new state: EXECUTING
2019-06-11 16:30:54,610 : DEBUG : KNIME-WFM-Parent-Notifier : NodeContainer : : : ROOT has new state: EXECUTING
2019-06-11 16:30:54,610 : DEBUG : KNIME-Worker-6 : WorkflowManager : Table Reader : 0:1 : Table Reader 0:1 doBeforePreExecution
2019-06-11 16:30:54,610 : DEBUG : KNIME-Worker-6 : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: PREEXECUTE
2019-06-11 16:30:54,610 : DEBUG : KNIME-Worker-6 : WorkflowManager : Table Reader : 0:1 : Table Reader 0:1 doBeforeExecution
2019-06-11 16:30:54,611 : DEBUG : KNIME-Worker-6 : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: EXECUTING
2019-06-11 16:30:54,611 : DEBUG : KNIME-Worker-6 : WorkflowDataRepository : Table Reader : 0:1 : Adding handler 62a8d990-859e-4427-8b08-fad4da6508c0 (Table Reader 0:1: <no directory>) - 1 in total
2019-06-11 16:30:54,611 : DEBUG : KNIME-Worker-6 : LocalNodeExecutionJob : Table Reader : 0:1 : Table Reader 0:1 Start execute
2019-06-11 16:31:11,712 : DEBUG : KNIME-Worker-6 : Buffer : Table Reader : 0:1 : Opening input stream on file "C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\knime_container_20190611_3385345473703860701.tmp", 0 open streams
2019-06-11 16:31:11,716 : DEBUG : KNIME-Worker-6 : Buffer : Table Reader : 0:1 : Using table format org.knime.core.data.container.DefaultTableStoreFormat
2019-06-11 16:31:11,730 : DEBUG : KNIME-TableIO-1 : Buffer : Table Reader : 0:1 : Forcing buffer to disc as it contains file store cells that need special handling
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WriteFileStoreHandler : Table Reader : 0:1 : Duplicating file store objects - file store handler id 06b04691-195c-4d8e-a9ae-1556c71f7480 is unknown to org.knime.core.node.workflow.WorkflowDataRepository
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WriteFileStoreHandler : Table Reader : 0:1 : Dump of valid file store handlers follows, omitting further log output
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WorkflowDataRepository : Table Reader : 0:1 : Valid file store handlers are:
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WorkflowDataRepository : Table Reader : 0:1 : --------- Start --------------
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WorkflowDataRepository : Table Reader : 0:1 : 62a8d990-859e-4427-8b08-fad4da6508c0 (Table Reader 0:1: <no directory>)
2019-06-11 16:31:11,731 : DEBUG : KNIME-TableIO-1 : WorkflowDataRepository : Table Reader : 0:1 : --------- End ----------------
2019-06-11 16:31:11,732 : DEBUG : KNIME-TableIO-1 : WriteFileStoreHandler : Table Reader : 0:1 : Assigning temp directory to file store "62a8d990-859e-4427-8b08-fad4da6508c0 (Table Reader 0:1: C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\fs-Table_0-1-26207)"
2019-06-11 16:31:12,567 : DEBUG : KNIME-Worker-6 : Buffer : Table Reader : 0:1 : Buffer file (C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\knime_container_20190611_9189562762371696835.bin.gz) is 0.065MB in size
2019-06-11 16:31:12,567 : INFO : KNIME-Worker-6 : LocalNodeExecutionJob : Table Reader : 0:1 : Table Reader 0:1 End execute (17 secs)
2019-06-11 16:31:12,567 : DEBUG : KNIME-Worker-6 : WorkflowManager : Table Reader : 0:1 : Table Reader 0:1 doBeforePostExecution
2019-06-11 16:31:12,567 : DEBUG : KNIME-Worker-6 : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: POSTEXECUTE
2019-06-11 16:31:12,567 : DEBUG : KNIME-Worker-6 : WorkflowManager : Table Reader : 0:1 : Table Reader 0:1 doAfterExecute - success
2019-06-11 16:31:12,567 : DEBUG : KNIME-Worker-6 : NodeContainer : Table Reader : 0:1 : Table Reader 0:1 has new state: EXECUTED
2019-06-11 16:31:12,568 : DEBUG : KNIME-Worker-6 : NodeContainer : Table Reader : 0:1 : KNIME_project 0 has new state: EXECUTED
2019-06-11 16:31:12,568 : DEBUG : KNIME-WFM-Parent-Notifier : NodeContainer : : : ROOT has new state: IDLE
2019-06-11 16:31:16,682 : DEBUG : main : OpenPortViewAction : : : Open Port View Table Reader (#1)
2019-06-11 16:31:16,706 : DEBUG : AWT-EventQueue-0 : Buffer : Table Reader : 0:1 : Opening input stream on file "C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\knime_container_20190611_9189562762371696835.bin.gz", 0 open streams
2019-06-11 16:31:31,124 : DEBUG : KNIME-Node-Usage-Writer : NodeTimer$GlobalNodeStats : : : Successfully wrote node usage stats to file: D:\KNIME\Olafs_workspace\.metadata\knime\nodeusage_3.0.json
2019-06-11 16:31:31,125 : DEBUG : KNIME-Node-Usage-Sender : NodeTimer$GlobalNodeStats : : : Sending of usage stats disabled.
2019-06-11 16:31:32,739 : DEBUG : main : WorkflowRootEditPart : : : WorkflowRootEditPart deactivated
2019-06-11 16:31:32,743 : DEBUG : main : WorkflowEditor : : : Disposing editor...
2019-06-11 16:31:32,744 : DEBUG : main : ProjectWorkflowMap : : : unregistering org.knime.workbench.editor2.WorkflowEditor@956cf3d from file:/D:/KNIME/Olafs_workspace/KNIME_project/. 0 left.
2019-06-11 16:31:32,744 : DEBUG : main : ProjectWorkflowMap : KNIME_project : 0 : Removing "file:/D:/KNIME/Olafs_workspace/KNIME_project/" from project map (0 remaining)
2019-06-11 16:31:32,744 : DEBUG : main : WorkflowManager : KNIME_project : 0 : Removing project "KNIME_project 0"
2019-06-11 16:31:32,746 : DEBUG : main : WorkflowDataRepository : Table Reader : 0:1 : Removing handler 62a8d990-859e-4427-8b08-fad4da6508c0 (Table Reader 0:1: C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\fs-Table_0-1-26207) - 0 remaining
2019-06-11 16:31:32,794 : WARN : main : WriteFileStoreHandler : Table Reader : 0:1 : Disposing file store "62a8d990-859e-4427-8b08-fad4da6508c0 (Table Reader 0:1: C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\fs-Table_0-1-26207)" - folder not or only partially deleted
2019-06-11 16:31:32,794 : DEBUG : main : ReadTableNodeModel : Table Reader : 0:1 : Removing all (0) views from model.
2019-06-11 16:31:32,794 : DEBUG : main : Node : Table Reader : 0:1 : clean output ports.
2019-06-11 16:31:32,795 : DEBUG : main : Buffer : Table Reader : 0:1 : Closing input stream on "C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\knime_container_20190611_9189562762371696835.bin.gz", 0 remaining
2019-06-11 16:31:32,795 : DEBUG : KNIME-Temp-File-Deleter : Buffer : : : Deleted temporary file "C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203\knime_container_20190611_9189562762371696835.bin.gz"
2019-06-11 16:31:32,797 : DEBUG : main : WorkflowManager : KNIME_project : 0 : Project "KNIME_project 0" removed (1 remaining)
2019-06-11 16:31:33,228 : INFO : KNIME-Worker-7 : WorkflowManager : KNIME_project : 0 : Could not delete temporary directory for workflow KNIME_project at C:\Users\User1\AppData\Local\Temp\4\knime_KNIME_project26203