Could not initialize class

I recently was given a new computer for work which is based on Windows 11 and seems to have more stringent security requirements than my old computer had. This caused problems with installing some nodes without security signatures, which we have resolved.

However, I am now encountering the following error when trying to use the CDK nodes:

ERROR Molecule to CDK 4:39 Execute failed: java.lang.NoClassDefFoundError: Could not initialize class org.openscience.cdk.knime.commons.CDKNodeUtils

I am on KNIME 5.5, CDK version 1.5.600.v202412052338

I would appreciate any insight into resolving this problem.

It looks like what is triggering my organisation’s overenthusiastic code integrity policy is specifically the jnati inchi wrapper used by the CDK nodes, but I’m no closer to finding a solution…