OK, thanks. I will take a look at this later.
Just a thought - did you select the ‘Delete FASTA Sequence column’ option? If not, then all 42k output rows will contain a copy of the whole 468k lines FASTA file, which will 1 - fill up your hard drive pretty effectively, and 2 - take a crazy amount of time to ever write the table to disk!
There maybe other issues with the way the node is written which come into play when handling files of this sort of size - I will take another look at that too, and it maybe possible to write a FASTA reader which solves all of the above problems at once without very much effort at all, similar to the other ‘Load … files’ nodes we have (e.g. this one - https://nodepit.com/node/com.vernalis.knime.io.nodes.load.xml.LoadLocalXmlFilesNodeFactory)
Steve