I am trying to deploy an existing python code into KNIME but I faced some issues while simply trying to change the type of a column (which had missing values). Normally this is not a hinderance in python.
@vishal2001 maybe you can provide us with a full example of what you want to do. The data transfer from knime to Python uses the arrow format. You might have to convert that to pandas.
Also you might want to check the handling of date and time variables.