How to plot a chemical space graph

[mpepper]

Hello,
I am wondering if there is any possible way to plot a graph like this within KNIME?

[armingrudd]

How to create a boundary in PCA/t-SNE plot?

Hello, I am wondering if there is any possible way to plot a graph, like the one in link below, within KNIME? Any help/suggestions would be appreciated. Figure - PMC (nih.gov)