Pains Filters

This is a companion discussion topic for the original entry at

Dear Community,
How are classified the 3 PAINS families (A-B-C) in the RDKit Molecule Catalog Filter?
Thank you in advance!

These seem to be standard filters, but I’m not a chemist so I can’t elaborate on details. Maybe @manuelschwarze or @greglandrum could shed some light?

You could also ask in the dedicated subforum: