Pathway Enrichment Analysis

Groups Cheminformatics
1

Hi,
I tested a few gene subsets on this component as well as directly on the Reactome site, and received completely different results.
Is there a way to closer analyze this component?
Thanks,
-Aharon

2

Hi @zikook ,
Welcome to the KNIME Community!
Could you please let us know which component you want to look at more closely?

Here’s a detailed guide on how to work with the Components, and I think this might help you.

Thanks,
Sanket

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3

Hi,
Thank you for the guide.
I want to analyze the “Pathway Enrichment Analysis” component, as the results differed from performing the enrichment directly on the reactome site.
Regards
-Aharon

4

Hello @zikook,

Differences can arise due to input formats, parameters, or preprocessing to name some. Could you share more details on the discrepancies?

You might find this blog post helpful: Analyzing Gene Expression Data with KNIME

Best,
Keerthan

1 Like