There have been several posts about the meaning of the RDKit descriptors, for example this one:
(I’m going to tag @Aaron_Hart and @greglandrum as they were in the original discussion there, along with @manuelschwarze in case it’s useful!)
Having encountered the same question, I created a component which is now available on the KNIME hub at
You need the @Vernalis extensions installed to make this work (along with the RDKit nodes - but I assume if you run into this problem you have those already!)
The output contains a ‘Descriptions’ column, along with a collection column of the column names (This is needed because some of the descriptors return several columns - obviously you can Ungroup if you need a list of all the individual column names or use the Collection to String node if you want a simple string representation of them all in a single cell, e.g. to include in a report)
Steve