Dear all, I just tried to use the Ertl Scaffold Keys node for the first time today, inputting a list of 585 substances (as SMILES), and the node simply crashes (i.e. KNIME completely crashes) without warning after ca. 8% of execution (very reproducible). I am currently running KNIME 5.4.3 with Vernalis Version Vernalis Research, UK Vernalis Core-extension for KNIME Workbench 1.38.0.v202503121017 OS is Win 11 24H2. Any idea what might be going on? Thanks Joachim

Fixed in v1.38.2 - see: [image] Vernalis community updated to v1.38.2 - segfault fix with Ertl Scaffold Node Community Extensions We have release v1.38.2 of our community contribution with a fix to the Ertl Scaffold Keys node ( Ertl Scaffold Keys – KNIME Community Hub ) In rare cases, selecting the ‘Visualise Keys’ option with this node could cause a segmentation fault - thanks to @Jo1607 for reporting this: This was due to a bug in the underlying RDKit toolkit (thanks to @ptosco_w for identifying the cause - it will be fixed as part of the next RDKit release, but this patch avoids the problem immediately with this node… Thanks again for reporting, Steve

Vernalis Ertl Scaffold Keys Node crashes

Community Extensions

Vernalis April 22, 2025, 10:02am 8

Fixed in v1.38.2 - see:

Thanks again for reporting,

Steve